Status:

RECRUITING

Experimental Pain in Parkinsons

Lead Sponsor:

University of Aarhus

Collaborating Sponsors:

Aarhus University Hospital

Conditions:

Pain

Parkinson Disease

Eligibility:

All Genders

Phase:

NA

Brief Summary

Study comparing pain intensity and discomfort in patients with Parkinson´s disease and healthy controls during inducement of mechanical, thermal, and chemical experimental pain

Detailed Description

Project: Inducing experimental muscle pain in healthy volunteers, patients with Parkinson's disease in levodopa treatment, and patients with Parkinson's disease with deep brain stimulation treatment ...

Eligibility Criteria

Inclusion

  • Inclusion criteria
  • Group healthy volunteers: healthy subjects with no PD diagnosis
  • Group PD patients levodopa: Include PD patients treated with levodopa
  • Group PD patients DBS: Include PD patients with DBS Exclusion criteria
  • Known other neurological or medical disorders (e.g., stroke, neuropathy, diabetes) or other disorders with expected influence on experimental pain
  • Known dementia (a score \<24 on the MoCA)
  • Known untreated depression (a score ≥15 on the Beck Depression Inventory)
  • Unable to cooperate
  • Treated with painkillers except paracetamol and NSAID (except if pain and treatment is ad-equately stable as evaluated by a doctor)

Exclusion

    Key Trial Info

    Start Date :

    June 7 2023

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    January 1 2028

    Estimated Enrollment :

    63 Patients enrolled

    Trial Details

    Trial ID

    NCT05981261

    Start Date

    June 7 2023

    End Date

    January 1 2028

    Last Update

    August 8 2023

    Active Locations (1)

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    aarhus university Hospital

    Aarhus, Denmark, 8000