Status:

COMPLETED

Comparative Analysis of the Lung Inflammatory Response After Thoracic Surgery With Single or Double Lung Ventilation: a Randomized, Pilot, Trial

Lead Sponsor:

Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude

Conditions:

Thoracic Diseases

Surgery

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The goal of this clinical trial is to compare in patients undergoing thoracic procedures the lung inflammatory response in on one-lung ventilation and two-lung ventilation strategies The main question...

Eligibility Criteria

Inclusion

  • A diagnosis of pleural or mediastinal pathology that requires diagnostic or therapeutic surgical intervention;
  • Written consent to participate

Exclusion

  • Pregnant women;
  • Patients on mechanical ventilation prior to the procedure;
  • Patients classified by the American Society of Anesthesiology (ASA) as class 4;
  • Patients with subpulmonary or diaphragmatic pathologies, where it is believed that the two pulmonary technique is superior;
  • Impossibility of using a double-lumen tube or difficult intubation;
  • Patient does not support one-lung ventilation;
  • Patient with previous lung resection surgery

Key Trial Info

Start Date :

July 20 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2023

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05982639

Start Date

July 20 2023

End Date

December 1 2023

Last Update

May 8 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital Azambuja

Brusque, Santa Catarina, Brazil, 88353-902