Status:
UNKNOWN
Clinical Evaluation and Antimicrobial Effect of Papain Based Chemo-mechanical Caries Removal Agents
Lead Sponsor:
Alexandria University
Conditions:
Dental Caries
Eligibility:
All Genders
8-10 years
Phase:
NA
Brief Summary
Minimally invasive dentistry continues to gain importance, especially in the treatment of permanent teeth with deep caries lesions and immature roots. Chemo-mechanical caries removal (CMCR) is an alte...
Detailed Description
All the lesions in the children's oral cavity indicated for treatment will be treated and sampled for microbiological analysis prior to and following caries removal. On the day of the intervention, th...
Eligibility Criteria
Inclusion
- Healthy children aged 8-10 years old.
- The presence of at least one deep carious class 1 lesion in the first permanent molar with a score of 5 or 6 according to the International Detection and Assessment System (ICDAS), detected by visual-tactile inspection to assess lesion severity
Exclusion
- Children reporting spontaneous or elicited pain from caries or showing any signs of pulpal infection, swelling or abscess.
- Pulpal exposure or bleeding during the excavation procedure
- Children presenting with special health care needs or undergoing medical treatment for chronic or acute diseases affecting salivary flow.
- Allergy or sensitivity to any of the materials included in the study
Key Trial Info
Start Date :
April 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT05983900
Start Date
April 1 2023
End Date
June 1 2024
Last Update
April 2 2024
Active Locations (1)
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1
Faculty of Dentistry
Alexandria, Egypt