Status:

UNKNOWN

Subtyping of Insomnia Disorders Based on Multidimensional Features

Lead Sponsor:

Shanghai Mental Health Center

Conditions:

Insomnia Disorder

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Based on real world and focusing on patients with chronic sleep disorders, this study conducts a data-driven subtyping research on the clinical symptoms, polysomnography, near-infrared scanning, molec...

Eligibility Criteria

Inclusion

  • Aged between 18 and 65 years, regardless of gender;
  • Currently meeting the diagnostic criteria for insomnia disorder according to the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5);
  • Pittsburgh Sleep Quality Index (PSQI) total score ≥ 10;
  • Sufficient level of education and comprehension to complete the required examinations and assessments for this study;
  • Voluntarily participating in this research and signing the informed consent form.

Exclusion

  • Currently diagnosed with other sleep disorders (sleep-related breathing disorders, periodic limb movement disorder, parasomnias, central disorders of hypersomnolence, circadian rhythm sleep-wake disorders, etc.);
  • Currently diagnosed with organic brain diseases (epilepsy, cerebrovascular disease, etc.) or other organic diseases;
  • Patients with a history of or currently diagnosed with bipolar and related disorders, obsessive-compulsive and related disorders, schizophrenia spectrum and other psychotic disorders, trauma and stressor-related disorders, dissociative disorders, or eating disorders;
  • Women who are pregnant, breastfeeding, or planning to become pregnant during the study period;
  • Insomnia caused by alcohol or substance abuse;
  • High suicide risk, with HAMD-17 suicide factor score \> 2;
  • Inability to cooperate with near-infrared examinations and polysomnography due to physical conditions such as head injury, etc.

Key Trial Info

Start Date :

March 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2025

Estimated Enrollment :

216 Patients enrolled

Trial Details

Trial ID

NCT05985512

Start Date

March 1 2023

End Date

July 1 2025

Last Update

August 15 2023

Active Locations (1)

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Shanghai Mental Health Center

Shanghai, Shanghai Municipality, China, 200030