Status:

RECRUITING

Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection

Lead Sponsor:

Rush University Medical Center

Conditions:

Osteoarthritis of the Knee

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Prospective single-masked (study participant will be masked), randomized controlled trial to examine the influence of BMAC on patient-reported outcomes (PROs) in patients with primary knee osteoarthri...

Detailed Description

The purpose of this study is to examine the influence of BMAC on patient-reported outcomes (PROs) in patients with primary knee osteoarthritis and compare that to patients receiving corticosteroid inj...

Eligibility Criteria

Inclusion

  • Patients between the ages of 18-70
  • Long standing knee pain from osteoarthritis (KL grade 2-3) despite conventional treatments such as activity modification, weight loss, physical therapy, analgesics, nonsteroidal anti-inflammatory drugs, or injection therapy for at least 6 weeks
  • 7-day average pain score of at least 4 on VAS scale

Exclusion

  • Systemic diseases (Diabetes, malignancies, infections, etc.)
  • Post-traumatic arthritis
  • Patient had intra-articular injection on affected knee in last three months

Key Trial Info

Start Date :

July 19 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2028

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05985785

Start Date

July 19 2022

End Date

March 31 2028

Last Update

August 13 2025

Active Locations (1)

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1

Rush University Medical Center

Chicago, Illinois, United States, 60612