Status:

ACTIVE_NOT_RECRUITING

Study to Evaluate the Safety and Effectiveness of GP0116

Lead Sponsor:

Galderma R&D

Conditions:

Skin Manifestations

Eligibility:

All Genders

22+ years

Phase:

NA

Brief Summary

This is a prospective, randomized, evaluator-blinded, comparator-controlled, parallel group, multicenter study in the U.S. for correction of moderate to severe dynamic facial wrinkles and folds, such ...

Eligibility Criteria

Inclusion

  • Men and non-pregnant, non-breastfeeding women aged 22 years or older.
  • WSRS grade of 3 or 4 (moderate to severe folds) on each NLF as assessed by the Blinded Evaluator. The WSRS for each NLF does not need to be equal.
  • Intent to undergo treatment for correction of both left and right NLF.

Exclusion

  • Known/previous allergy or hypersensitivity to any injectable hyaluronic acid (HA) gel
  • Known/previous allergy or hypersensitivity to local anesthetics
  • Previous or present severe or multiple allergies manifested by severe reactions
  • Previous facial surgery near the treatment area

Key Trial Info

Start Date :

April 12 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2026

Estimated Enrollment :

186 Patients enrolled

Trial Details

Trial ID

NCT05987163

Start Date

April 12 2023

End Date

March 31 2026

Last Update

July 2 2025

Active Locations (19)

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Page 1 of 5 (19 locations)

1

Galderma Investigational Site (Site#8074)

Santa Monica, California, United States, 90404

2

Galderma Investigational Site (Site#8478)

Vista, California, United States, 92083

3

Galderma Investigational Site (Site#8680)

Westport, Connecticut, United States, 06880

4

Galderma Investigational Site (Site#8479)

Bradenton, Florida, United States, 34209