Status:

RECRUITING

BE WELL With Migraine: Brain Education and WELLness With Migraine

Lead Sponsor:

Wake Forest University Health Sciences

Collaborating Sponsors:

National Center for Complementary and Integrative Health (NCCIH)

Conditions:

Migraine

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this randomized clinical trial is to evaluate two different non-drug, virtual treatment options designed to improve the lives of patients with migraine. Both interventions involve 8 weekly...

Detailed Description

This study involves 8 weekly virtual sessions \& an online platform designed to improve the lives of patients with migraine. Participants from across the United States with migraine may be eligible to...

Eligibility Criteria

Inclusion

  • Diagnosis of migraine with or without aura by with headache frequency of 4-20 days/month
  • At least 1 year of migraine
  • At least 18 years old
  • Able to participate in 8 weekly online classes
  • Willingness to complete baseline headache logs
  • Headache-related disability (Headache Impact Test (HIT)-6) score \>50
  • Fluent in English
  • Completion of technology onboarding with the online platform
  • Pregnant women who are less than or equal to 16 weeks gestation at enrollment are allowed to participate

Exclusion

  • Major unstable medical/psychiatric condition that could be unsafe for participants or for the group environment.
  • Medication overuse headache, with migraine treatment
  • Pregnant women who are more than 16 weeks gestation at enrollment
  • Unstable migraine treatment at enrollment: any preventive treatment (oral or injectable medication or neuromodulatory device) started within 12 weeks OR acute treatment within 4 weeks to ensure stability
  • Unwillingness to maintain stable current medication dosages for study duration
  • Failure to complete baseline headache logs
  • Heavy alcohol and illicit drug use
  • Participation in another intervention clinical trial or one that would interfere in this study
  • Experience with stress reduction training (daily meditation practice, regular use of a mindfulness app, or prior experience with MBSR)
  • Any, and all other diagnoses or conditions which, in the opinion of the site investigator, would prevent the patient from being a suitable candidate for the study or interfere with the medical care needs of the study participant: COVID-positive test within 30 days of enrollment

Key Trial Info

Start Date :

July 31 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2027

Estimated Enrollment :

286 Patients enrolled

Trial Details

Trial ID

NCT05987592

Start Date

July 31 2024

End Date

June 30 2027

Last Update

May 29 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Cambridge Health Alliance - Center for Mindfulness and Compassion

Cambridge, Massachusetts, United States, 02141

2

Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States, 27157

3

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States, 45229-3039