Status:
COMPLETED
Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth
Lead Sponsor:
Cairo University
Conditions:
Necrotic Pulp
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
clinically compare the intensity of post-operative pain and the amount of bacterial load reduction after using 20% Epigallocatechin-3-gallate solution during chemomechanical preparation, versus 2.5% N...
Detailed Description
The patients will be randomly divided into 2 groups. Intervention group (20% epigallocatechin-3-gallate solution root canal irrigant) and control group (2.5% sodium hypochlorite root canal irrigant). ...
Eligibility Criteria
Inclusion
- The inclusion criteria:
- Systematically healthy patient (ASA I, II).
- Age between 18 and 45 years
- Male or female.
- Asymptomatic mandibular premolar teeth diagnosed with pulp necrosis.
- The exclusion criteria:
- Medically compromised patients having significant systemic disorders. (ASA III or IV).
- Teeth with:
- Immature roots
- Association with swelling or sinus tract.
- Acute peri-apical abscess or acute exacerbation of a chronic abscess.
- Mobility Grade II or III
- Previously accessed or endodontically treated
- Deep periodontal pockets more than 4 mm
- Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions.
- Patients who could not interpret the NRS.
Exclusion
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 30 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05988788
Start Date
October 1 2023
End Date
July 30 2024
Last Update
January 10 2025
Active Locations (1)
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1
Dentistry
Cairo, Egypt