Status:
COMPLETED
Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients
Lead Sponsor:
University Hospital Ostrava
Conditions:
Respiratory Distress Syndrome, Acute
Respiratory Insufficiency
Eligibility:
All Genders
18+ years
Brief Summary
This prospective, blinded observational clinical study was aimed to determine the effect of hyperhydration and muscle loss measured by Bioelectrical impedance vector analysis (BIVA) on mortality. The ...
Detailed Description
Hyperhydration has a detrimental effect on mortality risk and morbidity, increases the risk of acute kidney failure, the need of renal replacement therapy (RRT), worsens recovery of renal functions an...
Eligibility Criteria
Inclusion
- Patients with respiratory insufficiency, with the assumption of at least 7 days of artificial lung ventilation (medical, trauma, surgical patients)
- Primary acute respiratory distress syndrome (ARDS) (pulmonary involvement): pneumonia, inhalation trauma, chest trauma (lung contusion), aspiration
- Secondary ARDS (extrapulmonary): sepsis, shock states, acute pancreatitis, polytrauma, burns, non-cardiogenic shock, intoxication, TRALI (massive blood transfusion), drowning
- Patients with acute exacerbation of chronic obstructive pulmonary disease (COPD)
Exclusion
- Patients with unfavorable prognosis
- APACHE II ≥30
- Metastatic malignancy
- Conditions after cardiopulmonary resuscitation (KPCR) before admission
- Cerebral edema
- Brain trauma
- Intracranial hypertension
- Liver cirrhosis
- A pre-existing neurodegenerative disease
- Patients with pacemakers, defibrillators, pregnancy (conditions contraindications to use of bio-electrical impedance).
Key Trial Info
Start Date :
March 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 31 2022
Estimated Enrollment :
61 Patients enrolled
Trial Details
Trial ID
NCT05991778
Start Date
March 1 2021
End Date
May 31 2022
Last Update
August 15 2023
Active Locations (1)
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1
University Hospital Ostrava
Ostrava, Czech Republic, Czechia, 70852