Status:
COMPLETED
Digital Phenotyping and Lifestyle Intervention in Patients with Myasthenia Gravis
Lead Sponsor:
Uppsala University
Conditions:
Myasthenia Gravis
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Myasthenia Gravis (MG) is a chronic autoimmune neurological disorder where an antibody attack of muscle receptors causes fatigable skeletal muscle weakness. In addition to fatigue, several MG patients...
Detailed Description
The cohort is Myasthenia Gravis (MG) patients in Sweden. The primary research question is: can digital lifestyle intervention in an online-group format improve fatigue as measured by MG-ADL in MG pati...
Eligibility Criteria
Inclusion
- The MG disease status must be stable for at least six months before entry into the study; thus, the duration of the disease must be at least six months.
- Both patients with ocular and generalized MG are allowed to participate.
- For practical reasons, participants need to be able to understand fully and communicate in Swedish.
Exclusion
- Participation in another clinical trial in the past 6 months.
- Disease duration less than 6 months.
- Contraindications to physical activity: unstable coronary syndrome or myocardial infarction within the preceding three months, respiratory failure (vital capacity \< 70% predicted value) or cardiac failure (ejection fraction \< 50% predicted value), concomitant neuromuscular diseases, disabling rheumatological disease (\> 80% disability on the Barthel scale), chronic pain or disabling orthopedic conditions, hospitalization in the last three months for a serious medical or surgical condition, anemia (hematocrit \< 30%), stroke within the previous year.
- MG patients already performing moderate-intensity physical activity of 150min or more per week, i.e., one of the target interventions.
- Pregnancy.
Key Trial Info
Start Date :
July 10 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2025
Estimated Enrollment :
83 Patients enrolled
Trial Details
Trial ID
NCT05992025
Start Date
July 10 2023
End Date
March 15 2025
Last Update
March 30 2025
Active Locations (1)
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1
Uppsala University
Uppsala, Sweden, 75185