Status:
RECRUITING
Deconstructing Post Stroke Hemiparesis
Lead Sponsor:
Providence VA Medical Center
Conditions:
Stroke
Eligibility:
All Genders
18-90 years
Brief Summary
TRACTs (DeconsTructing Post StRoke HemipAresis for PreCision NeurorehabiliTation) is a single timepoint study that aims to deconstruct post-stroke deficits of the upper extremity into distinct compone...
Detailed Description
Veterans will be recruited through the Providence Veterans Affairs Medical Center and will have research visits at the Providence VA Center for Neurorestoration and Neurotechnology (CfNN, centerforneu...
Eligibility Criteria
Inclusion
- Diagnosis of a unilateral ischemic stroke occurring \>6 months prior as documented in medical chart
- Upper extremity motor impairment as measured by Fugl-Meyer Upper Extremity Assessment ≤60
- Ability to follow simple instructions in English
Exclusion
- Greater than moderate difficulty using the arm and hand pre-dating the stroke as assessed by the questions adapted from the QuickDASH outcome measure score on any question \>= 3, which measures physical function and symptoms in people with difficulty using the arm and hand.
- Visual or auditory disorders resulting in the inability to see or hear, respectively, the stimuli presented as part of research sessions
- Inability to maintain a seated position for at least one hour
- Standard MRI exclusion (e.g., significant claustrophobia or inability to tolerate loud noises, cardiac pacemaker (unless MRI-safe), implanted device (deep brain stimulation) or metal in the brain, cervical spinal cord, or upper thoracic spinal cord)
- Standard (single-pulse) TMS exclusion which include (in addition to those listed for MRI) pregnancy/lactation/planning to become pregnant during the study, seizure disorder, and primary or secondary CNS tumors
Key Trial Info
Start Date :
September 5 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2027
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT05993221
Start Date
September 5 2023
End Date
September 1 2027
Last Update
June 6 2025
Active Locations (1)
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1
Providence VA Medical Center
Providence, Rhode Island, United States, 02908