Status:

UNKNOWN

Effect of Sodium Glucose Co-transporter 2 Inhibitors on Left Atrial Remodeling

Lead Sponsor:

Aswan University

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Investigators are going to assess direct effect of SGLT2 inhibitors on left atrial remodeling in participants with nonvalvular paroxysmal atrial fibrillation regardless of diabetes status.

Eligibility Criteria

Inclusion

  • with non-valvular paroxysmal atrial fibrillation (AF that terminates spontaneously or with intervention within seven days of onset).
  • Patient age 18-60 years.
  • Patients with Glomerular Filtration Rate (GFR) \>45 ml/min/1.73m2 (Cockcroft-Gault equation).
  • Patient with normal left atrium or dilated (diameter \<5 cm)

Exclusion

  • Patients \< 18 yrs old.
  • Patients with valvular heart diseases (Moderate to severe MS, severe AS, Prosthetic heart valves).
  • Patients with left atrium \> 5cm.
  • Patients with glomerular Filtration Rate (GFR) \<45 ml/min/1.73m2 (Cockcroft-Gault equation).
  • Patient with ischemic heart disease (previous MI, UA, PCI or CABG).
  • Patient with previous ischemic stroke.

Key Trial Info

Start Date :

August 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05993897

Start Date

August 1 2023

End Date

December 1 2024

Last Update

August 15 2023

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