Status:
COMPLETED
Pain Treatment With Combinations of NSAIDs
Lead Sponsor:
Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty
Conditions:
Postoperative Pain, Acute
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The search for new safe and effective methods of pain relief after surgery on large joints is still an urgent problem. The most optimal approach in the treatment of postoperative pain is the use of mu...
Detailed Description
This is 6 days, randomized, double blind, parallel group, single-center study in 105 subjects. The distribution into groups was carried out by sequentially alternating the set into 4 groups celecoxib ...
Eligibility Criteria
Inclusion
- The patients with diagnosis of osteoarthritis of the knee or hip joint (M15.0, M16, M17) after primary knee or hip arthroplasty.
- Informed consent.
Exclusion
- Patients who cannot cooperate with the trial.
- Pregnant or breast feeding women,
- Оpioid addiction,
- Contraindication to NSAIDs (allergy to NSAID, history of ulcer and gastrointestinal bleeding, liver failure, renal failure (eGRF \< 60 ml/kg/1,73m2) and chronic kidney disease 2-5, known thrombocytopenia (\<100 mia/L)
Key Trial Info
Start Date :
January 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2023
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT05994287
Start Date
January 1 2021
End Date
January 1 2023
Last Update
January 25 2024
Active Locations (1)
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1
Federal Center for Traumatology, Orthopedics and Endoprosthetics
Cheboksary, Chuvashskaya Respublika, Russia, 429500