Status:

UNKNOWN

Evaluation of Prognostic Potentials of Gingival Crevicular Fluid E-cadherin and Total Antioxidant Capacity

Lead Sponsor:

Ali A Abdulkareem

Conditions:

Periodontitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Ability to anticipate the outcomes of periodontal therapy at baseline visit is crucial to outline and customize a treatment plan with predictable outcomes and cost-effectiveness. Presence of diverse r...

Detailed Description

Loss of attachment and formation of periodontal pockets are hallmarks of periodontitis. The treatment approach is either by nonsurgical or surgical periodontal therapy or a combination of both dependi...

Eligibility Criteria

Inclusion

  • Systemically healthy adult patients (\> 18 years).
  • Periodontitis (interdental clinical attachment loss (CAL) detectable at ≥2 non-adjacent teeth, or buccal/oral CAL of ≥3mm with pocketing of \>3mm is detectable at ≥2 teeth). All patients should exhibit generalized periodontitis with pockets of PPD = 4 to 6 mm of any stage, unstable, and grade A to C. Only maxillary teeth with single root will be included.

Exclusion

  • Consumption of antibiotics or periodontal treatment 3-months prior to the study.
  • Pregnancy and lactation.
  • Smoker.
  • History of systemic disease e.g., diabetes mellitus.
  • Patients currently recruited in other trials.
  • Patients not willing to consent.
  • Periodontal pockets ≥ 7mm, active caries, endodontic problem.
  • Multi-rooted teeth will be also considered as exclusion reasons.

Key Trial Info

Start Date :

February 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 25 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05994885

Start Date

February 15 2023

End Date

December 25 2023

Last Update

August 16 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

College of Dentistry/ University of Baghdad

Baghdad, Iraq