Status:
RECRUITING
Changes in Inhibition and Valuation After Eating
Lead Sponsor:
Icahn School of Medicine at Mount Sinai
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Bulimia Nervosa
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims t...
Detailed Description
The overarching goal of this project is to test a neurocomputational model of BN that incorporates learning and decision-making components of control. The study combines functional magnetic resonance ...
Eligibility Criteria
Inclusion
- Female
- Aged 18 to 45 years
- Current BMI greater than or equal to 18.5kg/m2 but under 30kg/m2
- Right-handed
- English-speaking
- Additional Inclusion Criteria for Women with Bulimia Nervosa:
- Meet DSM-5 criteria for bulimia nervosa
Exclusion
- Medical instability
- Ongoing medical treatment, medical condition, or psychiatric disorder that may interfere with study variables or participation
- Shift work
- Pregnancy, planned pregnancy, or lactation during the study period
- Allergy to any of the ingredients in or unwillingness to consume the standardized meal or unwillingness to drink water during the fasting period
- Any contraindication for fMRI
Key Trial Info
Start Date :
December 12 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT05995496
Start Date
December 12 2023
End Date
December 31 2027
Last Update
January 30 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Center of Excellence in Eating and Weight Disorders at the Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10029