Status:

ACTIVE_NOT_RECRUITING

Cervical Cancer Screening Based on First-void Urine Self-sampling to Reach un(Der)-Screened Women: ScreenUrSelf Trial

Lead Sponsor:

Universiteit Antwerpen

Collaborating Sponsors:

Antwerp University Hospital (UZA)

Centre for Cancer Detection (CvKO)

Conditions:

Cervix Cancer

Cervical Intraepithelial Neoplasia

Eligibility:

FEMALE

31-64 years

Phase:

NA

Brief Summary

The goal of the ScreenUrSelf trial is to increase cervical cancer screening attendance and compliance to follow-up by offering a first-void urine self-sampling alternative to women who are currently n...

Detailed Description

Patient: In this population-based study we target real un(der)-screened women, i.e., women (31-64y) eligible for the Flemish population-based cervical cancer screening program without any cytology/his...

Eligibility Criteria

Inclusion

  • Eligible for cervical cancer screening within the organized Population-based Screening Program in Flanders:
  • Female
  • Residing in Flanders, Belgium
  • Not actively opted out of the organized cervical cancer screening program
  • No history of total hysterectomy (data available since 2002)
  • No (former) diagnosis of cervical or uterine cancer (data available as of 2008)
  • Not included in other CvKO pilot projects
  • No cervical result registered in the cytohistopathological register of BCR and no information in the administrative data from health insurance companies (IMA) on PAP smears taken for at least the last 6 years (i.e., two screening rounds)
  • 31-64 years old (birth year 1959-1992)

Exclusion

  • Being pregnant or 6 weeks postpartum (self-reported after receiving the study letter/package)
  • Participation during menstruation or within the 3 following days is a contraindication
  • Not able to understand the study materials and participation form (informed consent form)

Key Trial Info

Start Date :

May 25 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 30 2026

Estimated Enrollment :

48000 Patients enrolled

Trial Details

Trial ID

NCT05996783

Start Date

May 25 2023

End Date

September 30 2026

Last Update

June 13 2025

Active Locations (1)

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Universiteit Antwerpen

Edegem, Antwerp, Belgium, 2650