Status:
RECRUITING
Investigating Surprise Signals in the Anterior Insula
Lead Sponsor:
University Hospital, Geneva
Collaborating Sponsors:
University of Geneva, Switzerland
Conditions:
Drug Resistant Epilepsy
Healthy
Eligibility:
All Genders
18+ years
Brief Summary
The investigators propose a behavioral experiment with SEEG recording and stimulation, to both confirm the role of a brain region known as the anterior insula in identifying surprise, and disambiguate...
Eligibility Criteria
Inclusion
- 18 years or older
- Fluent in French or English
- Patient who suffers from potentially surgically remediable drug-resistant focal epilepsy
- Patient who requires evaluation with intracranial stereo-EEG electrodes and has them implanted in the anterior insula
- Patient who is able and willing to provide informed consent
Exclusion
- Severe concomitant psychiatric disease or major psychological distress
- Patients who have an implanted stimulation device (e.g. pacemaker, defibrillator, neurostimulator)
- Intellectual/neurological/psychiatric deficiencies\* or inability to understand or follow the procedure
- Visual/motor deficiencies which could affect task performance
- The presence of seizures during routine clinical stimulation of insular electrodes
- Failure to complete the pre-experiment task training
- As determined by their clinical evaluation.
Key Trial Info
Start Date :
January 15 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05997758
Start Date
January 15 2024
End Date
December 1 2025
Last Update
May 8 2024
Active Locations (1)
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1
Service de Neurologie, Dpt des Neurosciences cliniques HUG
Geneva, Switzerland, 1205