Status:

COMPLETED

Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography

Lead Sponsor:

Hilda Elizabeth Macías Cervantes

Conditions:

Diabete Type 2

Unstable Angina

Eligibility:

All Genders

18-75 years

Phase:

PHASE3

Brief Summary

Calcification of the coronary arteries is a direct sign of atherosclerotic disease of the coronary arteries and has been shown to be a strong predictor of the risk of cardiovascular diseases, includin...

Detailed Description

It is now well recognized that Coronary Artery Disease (CAD) is part of the spectrum of cardiovascular diseases (CVDs) that have common underlying risk factors and may manifest as myocardial infarctio...

Eligibility Criteria

Inclusion

  • Male and female patients over 18 years of age
  • Who meet the criteria of the fourth definition of infarction with and without ST segment elevation
  • Known with diabetes mellitus 2 or newly diagnosed diabetes according to ADA criteria

Exclusion

  • Patients diagnosed with Type 1 Diabetes Mellitus
  • Patients on chronic replacement therapy for renal function using peritoneal dialysis or hemodialysis or with GFR less than 30 ml / min / 1.73m2
  • Patients who have recently undergone immunosuppressive therapy
  • Patients with a history of recurrent urinary tract infection
  • Patients known to be allergic to SGLT-2 inhibitors
  • Patients presenting as sudden aborted death.
  • Patients who after percutaneous coronary intervention require orotracheal intubation or present a state of shock

Key Trial Info

Start Date :

June 21 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2023

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT05998525

Start Date

June 21 2021

End Date

June 1 2023

Last Update

August 21 2023

Active Locations (1)

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Unidad Medica de Alta Especialidad No. 1, Bajío

León, Guanajuato, Mexico, 37260,