Status:
RECRUITING
Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS)
Lead Sponsor:
Università Vita-Salute San Raffaele
Conditions:
Acute Respiratory Distress Syndrome
Barotrauma
Eligibility:
All Genders
18+ years
Brief Summary
Barotrauma (pneumothorax, pneumomediastinum) is a well-described complication of Acute Respiratory Distress Syndrome (ARDS), especially in patients with coronavirus disease 2019 (COVID-19) (16.1% in C...
Detailed Description
Barotrauma occurs frequently in acute respiratory distress syndrome (ARDS), and has a difficult, non-standardized management. Unfortunately, mortality rates remain high (\> 60% in COVID-19 ARDS, aroun...
Eligibility Criteria
Inclusion
- Clinical and radiological signs of ARDS, according to Berlin criteria, requiring ICU admission;
- Obtain duly signed informed consent
- Availability of at least one chest CT scan during hospital stay
Exclusion
- • Poor quality imaging (because of motion/respiratory artefacts).
Key Trial Info
Start Date :
November 27 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2027
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT06001645
Start Date
November 27 2023
End Date
July 1 2027
Last Update
August 12 2025
Active Locations (4)
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1
A.O.U. di Cagliari
Cagliari, Italy
2
IRCCS San Raffaele Scientific Institute
Milan, Italy, 20132
3
A.O.U. Pisana
Pisa, Italy
4
Ospedale San Carlo
Potenza, Italy