Status:

COMPLETED

Rise Study for Depression

Lead Sponsor:

Big Health Inc.

Conditions:

Major Depressive Disorder

Eligibility:

All Genders

22+ years

Phase:

NA

Brief Summary

This study will examine the efficacy of digital CBT versus waitlist in improving symptoms for adults with Major Depressive Disorder.

Detailed Description

This study aims to examine the effectiveness of app-based digital CBT in individuals with a diagnosis of Major Depressive Disorder. The primary outcomes are depression symptom reduction and engagement...

Eligibility Criteria

Inclusion

  • Adults aged ≥22 years old
  • Score ≥10 and \<20 on the 8-item Patient Health Questionnaire (PHQ-8)
  • Diagnosis of Major Depression
  • Current resident of the USA
  • Oral and written fluency in English
  • Regular access to the internet via a mobile or tablet device using Android (5 or higher) or iOS (13 or higher)
  • Participant is able and willing to comply with protocol requirements, has been informed of the nature of the study, and has signed the IRB-approved informed consent form

Exclusion

  • Must not be currently receiving or be expecting to start therapy for depression, anxiety, or sleep during study participation, or have received cognitive behavioral therapy for depression, anxiety, or sleep in the past 12-months
  • If on psychotropic medication, this must be stable for at least 60 days
  • Past or present psychosis, schizophrenia, or bipolar disorder
  • Moderate or greater suicide risk
  • Treatment-resistant depression
  • Hearing or vision impairment that prevents effective use of the audio-visual content of digital CBT or psychoeducation
  • Intellectual disability or any Neurocognitive or Neurodevelopmental disorder that would prevent participants from following study procedures
  • Any condition that the investigator believes would make participation in the study not in the best interest of the subject or would preclude successful completion of study activities
  • Other exclusion criteria may apply

Key Trial Info

Start Date :

August 31 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 21 2023

Estimated Enrollment :

61 Patients enrolled

Trial Details

Trial ID

NCT06003361

Start Date

August 31 2023

End Date

December 21 2023

Last Update

January 17 2024

Active Locations (1)

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1

Big Health Inc.

San Francisco, California, United States, 94108