Status:
RECRUITING
The Effectiveness of the Letrozole-induced Endometrial Preparation Protocol in Frozen-thawed Embryo Transfer (FET)
Lead Sponsor:
International Peace Maternity and Child Health Hospital
Conditions:
Letrozole
Infertility, Female
Eligibility:
FEMALE
Up to 40 years
Phase:
NA
Brief Summary
The goal of this single center, non-blinded, randomized controlled clinical trial to comparison of pregnancy outcomes and perinatal outcomes in patients undergoing IVF treatment (including ICSI) with ...
Eligibility Criteria
Inclusion
- Women \<40 years of age undergoing IVF or ICSI at our reproductive center with a total of ≤3 superovulation cycles , and with ≥2 cleavage embryos or ≥1 blastocyst were cryopreserved. Previous cycles of embryo transfer ≤ 2 and only one transfer cycle with 1-2 embryos per study subject was enrolled.
Exclusion
- Patients with chromosomal abnormalities in either spouse, hydrosalpinx, severe endometriosis, adenomyosis, and uterine and uterine cavity organic diseases such as uterine malformations, endometrial polyps, and uterine adhesions;
- patients who underwent pre-implantation genetic diagnosis (PGT);
- patients who underwent ICSI using surgically obtained epididymal or testicular spermatozoa;
- patients with a Body mass index (BMI, = weight/height2 ) \> 30 kg/m2;
- patients with recurrent spontaneous abortions;
- patients with sequential embryo transfer.
Key Trial Info
Start Date :
August 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2027
Estimated Enrollment :
858 Patients enrolled
Trial Details
Trial ID
NCT06006091
Start Date
August 1 2023
End Date
August 1 2027
Last Update
August 23 2023
Active Locations (1)
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1
Yu Xiao
Shanghai, China