Status:

RECRUITING

An Observational Cohort Study to Characterize the Effectiveness and Safety of HEMGENIX® in Patients With Hemophilia B

Lead Sponsor:

CSL Behring

Conditions:

Hemophilia B

Eligibility:

All Genders

18+ years

Brief Summary

This observational, post-authorization, long-term follow-up study aims to investigate the short and long-term effectiveness and safety of HEMGENIX in patients with hemophilia B. The study will also in...

Eligibility Criteria

Inclusion

  • HEMGENIX Cohort:
  • \- Treatment with commercial HEMGENIX.
  • \- Have provided signed written informed consent within 3 months before or within 6 months after HEMGENIX treatment, or within 6 months of when the study is initiated at the participating site.
  • FIX Prophylaxis Cohort:
  • \- Adult patients (≥ 18 years) with hemophilia B who have consented and enrolled in ATHN Transcends Hemophilia Cohort (or a similar registry) and are receiving FIX prophylaxis therapy.

Exclusion

  • HEMGENIX Cohort:
  • \- The patient population that will be observed in this study must not have been treated with etranacogene dezaparvovec in a clinical trial.

Key Trial Info

Start Date :

June 15 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 1 2043

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT06008938

Start Date

June 15 2023

End Date

August 1 2043

Last Update

December 26 2025

Active Locations (10)

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Page 1 of 3 (10 locations)

1

American Thrombosis and Hemostasis Network

Rochester, New York, United States, 14604

2

Medical University Vienna

Vienna, Austria

3

Aarhus Universitetshospital

Århus N, Denmark

4

Centre Hospitalier Universitaire de Brest / CHU Morvan

Brest, France