Status:

RECRUITING

Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients

Lead Sponsor:

Massachusetts General Hospital

Conditions:

Fibromyalgia

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Fibromyalgia (FM) is a syndrome with clinical symptoms involving multiple systems. The efficacy of current treatments is inadequate, and more alternative modalities are needed for the management of FM...

Detailed Description

The main goal of this study is to generate preliminary data on the effect of VNS on FM symptoms. Specifically, the investigators will utilize a recently developed, non-invasive method of tVNS (transcu...

Eligibility Criteria

Inclusion

  • Subject is 18 to 80 years old, including both male and female subjects.
  • Subject has a documented diagnosis of FM for at least three months. This requirement is to avoid the uncertainty of an unstable pain condition and to minimize the study variation.
  • Subject has a pain score of 4 or above (numeric pain score: 0 - 10 from no pain to worst pain).

Exclusion

  • Subject has current cardiac arrhythmia or had implanted cardiac pacemaker or AICD device.
  • Subject has major psychiatric disorder required hospitalization in the last 3 months.
  • Subject has active infection at the site of device application.
  • Subject has recurrent syncope symptoms within the past three months.
  • Subject is pregnant.
  • Subject has had VNS treatment within the past two months.
  • .

Key Trial Info

Start Date :

July 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 31 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06009159

Start Date

July 1 2024

End Date

October 31 2026

Last Update

May 6 2025

Active Locations (1)

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1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114