Status:
COMPLETED
Evaluation of Serum Levels of C Reactive Protein (CRP) and Its Correlation With Fetal Ultrasound Parameters in the Prediction of Threatened Miscarriage in the First Trimester
Lead Sponsor:
Al-Azhar University
Conditions:
Threatened Miscarriage
Eligibility:
FEMALE
20-35 years
Brief Summary
The goal of this observational study is to evaluate and compare in pregnant women with threatened miscarriage in the first trimester. The main questions it aims to answer are: What is the correlation...
Detailed Description
This observational study will enroll 100 pregnant women, with 50 in the threatened miscarriage group and 50 healthy controls, to compare serum C reactive protein (CRP) levels and fetal ultrasound find...
Eligibility Criteria
Inclusion
- All pregnant women in the age group (20-35) between 7 and 13 weeks gestation in which a singleton embryo with evident cardiac activity with sure last menstrual period (LMP) constant with 1st trimester documented ultrasound
- The included subjects will be divided into two groups:-
- Group 1 (control) will consist of 50 pregnant women with uneventful pregnancies without any problem.
- Group 2 (patients) will consist of 50 pregnant women with threatened miscarriage, of them.
Exclusion
- Multiple pregnancies.
- Women having received hormonal treatment or progesterone supplements.
- Pregnancies with a difference of more than 7 days between last menstrual period (LMP) and crown- rump length.
- History of general medical disease e.g. diabetes, thyroid disease or antiphospholipid syndrome, Presence of local (gynecological) disease e.g. fibroid or adnexal masses verified by normal appearance of the uterus and ovaries by ultrasound.
- Presence of uterine malformations e.g. hypoplastic uterus or septate uterus diagnosed by history of recurrent miscarriage, hysterosalpingography or 3D ultrasound, Intake of natural or synthetic progesterone.
- Obesity.
- Ectopic pregnancy
- Vesicular mole
- Fetal demise by Ultrasound
Key Trial Info
Start Date :
July 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2023
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06011057
Start Date
July 1 2022
End Date
October 1 2023
Last Update
December 12 2023
Active Locations (1)
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1
Al-Hussein University Hospital
Cairo, Egypt, 11633