Status:

COMPLETED

An Observational Cohort Study to Describe and Compare the Use of Darolutamide, Enzalutamide and Apalutamide and How Well These Work in Men With Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) in Real World Settings

Lead Sponsor:

Bayer

Conditions:

Non-metastatic Castration-resistant Prostate Cancer

Eligibility:

MALE

18+ years

Brief Summary

This is an observational cohort study in men with non-metastatic castration-resistant prostate cancer who received their usual treatment, which is 'Androgen receptor inhibitors' (ARIs) including darol...

Eligibility Criteria

Inclusion

  • Men diagnosed with prostate cancer.
  • Diagnosis of nmCRPC prior to or within 90 days after the first ARI treatment initiation
  • Treatment with Darolutamide, Enzalutamide, or Apalutamide initiated for the first time
  • Age ≥ 18 years at treatment start
  • At least 6 months of Electro-Medical-Record activity after the treatment start unless the patient died earlier than 6 months.

Exclusion

  • Evidence of metastatic disease before or 30 days after treatment start
  • Prior history of other primary cancers

Key Trial Info

Start Date :

August 31 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 28 2024

Estimated Enrollment :

1375 Patients enrolled

Trial Details

Trial ID

NCT06013475

Start Date

August 31 2023

End Date

October 28 2024

Last Update

June 12 2025

Active Locations (1)

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1

Bayer

Whippany, New Jersey, United States, 07981