Status:
RECRUITING
Personalized Real-Time DBS and PD Mechanisms
Lead Sponsor:
David Escobar
Collaborating Sponsors:
The Cleveland Clinic
Conditions:
Parkinson Disease
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
A prospective cohort of patients scheduled to undergo deep brain stimulation (DBS) implantation surgery for the treatment of Parkinson's disease as per standard of care will be invited to participate ...
Detailed Description
While much research has been dedicated to understanding the pathophysiology of Parkinson's disease (PD), the neural dynamics underlying the manifestation of motor signs remain unclear. Studies over th...
Eligibility Criteria
Inclusion
- Key
- Ability to provide informed consent.
- Clinical diagnosis of idiopathic Parkinson's disease.
- Determined, as per standard of care, to be a candidate for deep brain stimulation (DBS) surgery targeting the subthalamic nucleus.
- Ability to tolerate delays in taking daily standard Parkinson's disease medications.
- Key
Exclusion
- Secondary Parkinsonism, stroke, or progressive central nervous system disease other than Parkinson's disease.
- Patient has a condition that, in the opinion of the investigators, would significantly increase the risk of interfering with study compliance, safety, or outcome.
Key Trial Info
Start Date :
August 29 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2028
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT06013956
Start Date
August 29 2023
End Date
June 30 2028
Last Update
May 14 2025
Active Locations (1)
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1
Cleveland Clinic
Cleveland, Ohio, United States, 44195