Status:

UNKNOWN

Preoperative Nebulized Dexmedetomidine on Hemodynamic Changes in Laparoscopic Bariatric Surgery.

Lead Sponsor:

Tanta University

Conditions:

Dexmedetomidine

Hemodynamics

Eligibility:

All Genders

18-50 years

Phase:

NA

Brief Summary

This randomized study aims to evaluate the effect of preoperative dexmedetomidine nebulization on blunting hemodynamic response for laryngoscope, intubation and pneumoperitoneum in morbidly obese pati...

Detailed Description

Dexmedetomidine is an α -2 adrenergic agonist that has been proven to attenuate the hemodynamic response to intubation and pneumoperitoneum along with dose sparing effect on opioids and propofol .It h...

Eligibility Criteria

Inclusion

  • This study will include 90 adult morbidly obese patients of both sex with BMI (40-50), (ASA) III physical status, aged between 18 -50 years scheduled for elective laparoscopic bariatric surgery under general anesthesia.

Exclusion

  • Patient's refusal.
  • Decompensated hepatic or renal or cardiac disease.
  • Expected difficult airway management.
  • Uncontrolled hypertension.
  • Psychiatric disease.
  • Sever pulmonary disorders.
  • Patients on opioid, alcohol, beta-blockers or allergy to any of the study drugs.

Key Trial Info

Start Date :

August 27 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2024

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06014359

Start Date

August 27 2023

End Date

February 1 2024

Last Update

August 31 2023

Active Locations (1)

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1

Tanta University

Tanta, ElGharbia, Egypt, 31527