Status:

RECRUITING

The Effect of Preoperative Maxigesic® on Intraoperative Remifentanil Requirement

Lead Sponsor:

Ajou University School of Medicine

Conditions:

Opioid Use

Eligibility:

All Genders

19-60 years

Phase:

NA

Brief Summary

Maxigesic is combined intravenous analgesic of ibuprofen and acetaminphen. The purpose of this study is investigate weather preoperative Maxigesic administration can reduce intraoperative remifentanil...

Detailed Description

Remifentanil is an ultra-short-acting opioid that is useful during surgery because of its fast onset and recovery. However, because of this profile, it is known that the use of high doses of remifenta...

Eligibility Criteria

Inclusion

  • Adult patients (19-60 years old) with ASA physical status 1, 2, 3
  • Scheduled surgery under general anesthesia

Exclusion

  • The patient does not conset
  • Pregnancy
  • hepatic disorder
  • Renal disorder
  • Asthma
  • Hypersensitivity to the NSAIDs or acetaminophen
  • Patients receiving chronic pain therapy
  • Drug dependence
  • Patients taking psychiatric drugs
  • Alcoholics
  • History of gastrointestinal ulcer or bleeding

Key Trial Info

Start Date :

August 30 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT06015711

Start Date

August 30 2023

End Date

December 31 2026

Last Update

October 3 2025

Active Locations (1)

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Ajou university school of medicine

Suwon, Gyeonggi-do, South Korea, 16499