Status:

UNKNOWN

Prevalence of ATTR Cardiac Amyloidosis in Patients Undergoing TAVR

Lead Sponsor:

Jordan Collaborating Cardiology Group

Conditions:

ATTR Amyloidosis Wild Type

Severe Aortic Stenosis

Eligibility:

All Genders

65+ years

Brief Summary

ATTR-cardiac amyloidosis (CA) is present in 4% to 16% of elderly patients with severe calcific aortic stenosis (AS). The reasons for this association are not fully known. It is hypothesized that an am...

Detailed Description

ATTR-cardiac amyloidosis (CA) is present in 4% to 16% of elderly patients with severe calcific aortic stenosis (AS). The reasons for this association are not fully known. Two hypotheses may explain th...

Eligibility Criteria

Inclusion

  • Age ≥65 years
  • Severe aortic stenosis
  • Patient underwent TAVR procedure
  • Positive pyruvate PO4 scan

Exclusion

  • Diagnosis of AL amyloidosis base on free light chain assay, serum and urine immune electrophoresis.

Key Trial Info

Start Date :

October 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06015997

Start Date

October 1 2023

End Date

November 1 2025

Last Update

August 29 2023

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