Status:
UNKNOWN
Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Lead Sponsor:
Tanta University
Conditions:
Postoperative Nausea and Vomiting
Laparoscopic Cholecystectomy
Eligibility:
FEMALE
18-65 years
Phase:
PHASE2
Brief Summary
The aim of the study is to compare antiemetic effects between dexmedetomidine and ondansteron in the first group versus dexamethasone and ondansteron in the second group. The primary outcome in this ...
Detailed Description
General anesthesia is widely used in several surgeries. It can cause some complications such as postoperative nausea and vomiting (PONV). PONV is more common in general anesthesia than spinal anesthes...
Eligibility Criteria
Inclusion
- 70 Female patients aged between 18 and 65 years
- ASA I or II
- patients scheduled for elective laparoscopic cholecystectomy surgery will be included in this study.
Exclusion
- Females above 65 years old.
- patients under 18 years old.
- ASA \> II.
- Obesity (BMI\>40 kgm2).
- Known hypersensitivity to drugs used in the study protocol.
- Comorbidities that were known to increase the risk of PONV (e.g. vestibular disease).
- Liver or renal dysfunction (liver enzyme or creatinine 1.5 times higher than normal).
- Alcoholism or drug abuse.
- Use of antiemetics and psychotropic drugs or glucocorticoids within 24 h before surgery.
Key Trial Info
Start Date :
September 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2023
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT06017167
Start Date
September 15 2022
End Date
October 1 2023
Last Update
August 30 2023
Active Locations (1)
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1
Tanta University hospitals
Tanta, Algharbia, Egypt, 31511