Status:
COMPLETED
Effects of Early and Late Time-restricted Eating on Overweight Adults With Metabolic Syndrome
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University
Conditions:
Metabolic Syndrome
Overweight and Obesity
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Investigators aim to compare the effects of early and late time-restricted feeding on overweight adults with metabolic syndrome
Eligibility Criteria
Inclusion
- Age from 18 to 65 years
- Body mass index (BMI): 24.0-40.0 kg/m2
- Diagnosed with metabolic syndrome (i.e., more than 3 abnormal findings out of 5):
- Waist circumference ≥ 90 cm (men) or ≥ 80 cm (women).
- Elevated triglyceride (TG) (use of lipid-lowering medication is an alternate indicator) ≥ 150 mg/dL (1.7 mmol/L).
- Reduced high-density lipoprotein cholesterol (HDL-c) (use of lipid-lowering medication is an alternate indicator) \< 40 mg/dL (1.0 mmol/L) in males \< 50 mg/dL (1.3 mmol/L) in females.
- Elevated blood pressure (use of antihypertensive medication is an alternate indicator). Systolic blood pressure (SBP) ≥ 130 and/or diastolic blood pressure (DBP) ≥ 85 mmHg.
- Elevated fasting blood glucose (FBG) (used of hypoglycemic medications is an alternate indicator) ≥ 100 mg/dL (5.6 mmol/L).
Exclusion
- Unstable weight (change \> 10% current body weight) for 3 months prior to the study
- Pregnant or breast-feeding
- Night shift workers
- History of major diseases or related diseases, such as cancer, inflammatory disease, chronic obstructive pulmonary disease and major adverse cardiovascular event
- Active viral hepatitis, acquired immune deficiency syndrome, syphilis and other sexually transmitted diseases, tuberculosis and other infectious diseases
- Being treated with antibiotics or corticosteroids
- Current participate in other weight-management program, current on a prescribed diet for special disease or current on any drugs that effect appetite
- The researcher deemed it inappropriate to participate in the experimenter.
Key Trial Info
Start Date :
May 7 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 16 2024
Estimated Enrollment :
103 Patients enrolled
Trial Details
Trial ID
NCT06018415
Start Date
May 7 2024
End Date
October 16 2024
Last Update
December 22 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
First Affiliated Hospital of Xi 'an Jiaotong University
Xi'an, Shaanxi, China, 710061