Status:

UNKNOWN

Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity

Lead Sponsor:

Alexandria University

Conditions:

Neuroinflammatory Response

Nerve Injury

Eligibility:

All Genders

18+ years

Brief Summary

The aim of this observational study is to answer the following questions in individuals with acute and chronic exposure to organophosphates. The main questions to be addressed are 1. What are the pro...

Detailed Description

This is a cross-sectional study that aims to assess the possible prognostic value of markers of neuroinflammation and nerve damage in patients with acute and chronic exposure to organophosphate pestic...

Eligibility Criteria

Inclusion

  • For the control group: healthy individuals without previous exposure to organophosphates, with the specified age limits.
  • For the acute exposure group: patients with acute exposure to organophosphates, with the specified age limits
  • For the chronic exposure group: patients with chronic exposure to organophosphates, with the specified age limits
  • No restrictions on comorbidities in the three groups except those mentioned under Exclusion Criteria

Exclusion

  • Pediatric patients.
  • Patients with neurological diseases (Parkinsonism, epilepsy, Alzheimer's disease, etc.)
  • Patients who does not meet the inclusion criteria.

Key Trial Info

Start Date :

August 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2024

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06021262

Start Date

August 1 2023

End Date

January 1 2024

Last Update

September 1 2023

Active Locations (1)

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1

Alexandria Main University Hospital

Alexandria, Egypt