Status:

RECRUITING

GetUp&Go: A Randomized Controlled Trial of an Intervention to Enhance Physical Activity After TBI

Lead Sponsor:

Albert Einstein Healthcare Network

Collaborating Sponsors:

National Institute on Disability, Independent Living, and Rehabilitation Research

Conditions:

Traumatic Brain Injury

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to evaluate GetUp\&Go, a program for promoting increased physical activity in individuals at least 6 months post moderate-to-severe traumatic brain injury. GetUp\&Go...

Detailed Description

The investigators will conduct a Randomized Controlled Trial (RCT) of a novel, remotely delivered physical activity (PA) promotion program, called GetUp\&Go-a name selected by focus group participants...

Eligibility Criteria

Inclusion

  • Age ≥18
  • TBI (open or closed), sustained at least 6 months prior to enrollment, of at least complicated-mild/moderate severity as evidenced by loss or alteration of consciousness ≥ 30 minutes; and/or post-traumatic amnesia (PTA) ≥ 24 hours, not due to intoxication/sedation and documented prospectively from the injury; and/or positive neuroimaging findings consistent with TBI
  • Fully weight bearing on lower limbs and able to walk indoors and outdoors without the assistance of another person
  • Cognitively able to participate in treatment as judged by ability to travel independently within the community
  • Able to communicate adequately in English for participation in the treatment protocols
  • Informed consent given by participant

Exclusion

  • Contraindications to increasing PA as judged by study physician, using an exam based on published screening tools
  • Medical or psychiatric instability, including current psychosis or severe uncontrolled substance misuse, as assessed using items from the SCID/MINI/ASSIST, or suicidal ideation with intent or plan, as assessed by the Columbia-Suicide Severity Rating Scale, screening version
  • Significant physical or intellectual disability predating the TBI
  • Neurodegenerative disorder, e.g., Parkinson's disease
  • Insufficiently inactive, i.e., reporting \> 23 weekly moderate/vigorous activity units on the Godin Leisure-Time Exercise Questionnaire
  • Planned surgery or other hospitalization during the succeeding 9 months
  • Physical or sensory disability (e.g., blindness; severe bimanual incoordination) that prevents use of a smartphone

Key Trial Info

Start Date :

December 19 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 31 2027

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT06028334

Start Date

December 19 2023

End Date

August 31 2027

Last Update

March 20 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Moss Rehabilitation Research Institute

Elkins Park, Pennsylvania, United States, 19027

GetUp&Go: A Randomized Controlled Trial of an Intervention to Enhance Physical Activity After TBI | DecenTrialz