Status:
COMPLETED
Black Seed Oil in Treatment of Osteoarthritis
Lead Sponsor:
Ramsar international campus
Conditions:
Osteo Arthritis Knee
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
Osteoarthritis is a continual illness of joints. We aim to investigate the effect of Nigella sativa oil in comparison with placebo on the reduction of osteoarthritis pain. This study is a double-blin...
Detailed Description
This study was a randomized controlled trial. Regarding to the inclusion criteria, 110 osteoarthritis patients were included in this study based on clinical signs, physical examination and radiologica...
Eligibility Criteria
Inclusion
- unilateral or bilateral involvement of one or more joints for over 4 months,
- ability to walk
- ability to stay throughout the study period
- no history of underlying inflammatory disease (arthropathy / rheumatoid arthritis),
- absence of diabetes,
- no history of allergy to black seed
- absence of hyperuricemia (\<338 umol/l) or history of gout,
- absence of recent injury and trauma to the joint with osteoarthritis,
- absence of intra articular injection of corticosteroids in the last 4 months,
- lack of sensitivity to NSAIDS,
- no underlying liver and kidney disease or history of peptic ulcer Or gastrointestinal bleeding, Congestive Heart Failure, hypertension, and hyperkalemia ,
- no fever
- absence of obvious Complete Blood Count disorders, coagulopathy, hematologic or neurological disorders ,
- no alcohol consumption
Exclusion
- pregnancy,
- breast feeding,
- pregnancy-related decision
- obesity (BMI\> 30 kg /m2).
Key Trial Info
Start Date :
January 14 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 12 2020
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT06029868
Start Date
January 14 2019
End Date
February 12 2020
Last Update
September 8 2023
Active Locations (1)
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1
Ramsar international campus
Ramsar, Mazandaran, Iran