Status:
RECRUITING
Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women
Lead Sponsor:
Linkoeping University
Collaborating Sponsors:
Region Östergötland
Länssjukhuset i Kalmar län
Conditions:
Postmenopausal Symptoms
Hot Flashes
Eligibility:
FEMALE
45+ years
Phase:
NA
Brief Summary
The goal of this randomised controlled trial is to investigate the effects of and compare two modes of physical exercise (strength training and high-intensity aerobic exercise) to unchanged physical a...
Detailed Description
The overall aim is to investigate the efficacy of and compare two modes of physical exercise (strength training and high-intensity aerobic exercise) to unchanged physical activity on vasomotor symptom...
Eligibility Criteria
Inclusion
- Postmenopausal women (one of: ≥ 12 months since last menstruation; amenorrhea due to intrauterine device or hysterectomy and Follicle Stimulating Hormone (FSH) \>30 mIU/ml; bilateral oophorectomy; induced menopause due to chemotherapy or radiation and ≥2 years amenorrhea);
- ≥ 28 moderate to severe hot flushes per week during a 2-week screening period, registered through a daily VMS diary;
- Age ≥45 years;
- Physical ability to participate in strength training or high intensity aerobic exercise for 60 minutes, 3 times/week during 15 weeks;
- Understand Swedish orally and in writing
Exclusion
- Regular physical activity \>30 minutes per week of vigorous intensity or ≥150 minutes of moderate intensity or combined activities representing maximum 150 minutes of moderate intensity;
- Use of systemic menopausal hormone therapy the last 2 months;
- Use of natural preparations such as herbal preparations for VMS, or other medications for VMS the last 2 months;
- Capillary hemoglobin \<110 g/l;
- Blood pressure \>160 mmHg systolic or \>100 mmHg diastolic;
- Unstable medical condition with a potential to affect VMS (like unregulated thyroid disease);
- Medical condition that by a physician is judged not appropriate (because of potential to affect VMS or risk of injury with vigorous exercise)
Key Trial Info
Start Date :
September 12 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2032
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06030388
Start Date
September 12 2023
End Date
December 1 2032
Last Update
January 22 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Region Kalmar Län
Kalmar, Sweden, S-39126
2
Region Östergötland
Linköping, Sweden, S-58185