Status:
COMPLETED
Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome
Lead Sponsor:
University Medical Center Groningen
Conditions:
Microbial Colonization
Antibiotic Side Effect
Eligibility:
All Genders
Up to 1 years
Phase:
NA
Brief Summary
In this study, investigators seek to determine whether the timing of antibiotics given to mothers during an elective C-section affects the composition of their infant's gut microbiome. To do this, a r...
Detailed Description
Rationale: During a caesarean delivery, umbilical cord clamping can occur before or after administering a perioperative prophylactic antibiotic to the mother. If the cord is clamped before the antibio...
Eligibility Criteria
Inclusion
- Females undergoing elective CS at the UMCG
- Gestational age in weeks equal to or above 38 weeks
Exclusion
- Cephalosporin allergy
- Exposure to antibiotic agent 2 weeks before CS
- Temperature \>37.5 C before CS
- Pre-labour rupture of membranes
- Emergency CS
- No -20 freezer at home
- No command of the Dutch language
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2023
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT06030713
Start Date
March 1 2019
End Date
March 1 2023
Last Update
September 13 2023
Active Locations (1)
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1
University Medical Center Groningen
Groningen, Netherlands, 9713 GZ