Status:
COMPLETED
Thyroxine Therapy for Recurrent Pregnancy Loss in Hypothyroid Women
Lead Sponsor:
Al-Kindy College of Medicine
Collaborating Sponsors:
Al-Elwyiah Maternity Teaching Hospital
Conditions:
Recurrent Early Pregnancy Loss
Thyroid Diseases
Eligibility:
FEMALE
18-40 years
Phase:
PHASE3
Brief Summary
The goal of this clinical trial is to investigate the influence of thyroxine supplementation on pregnancy outcomes in women with varying levels of Thyroid-Stimulating Hormone (TSH), who have experienc...
Detailed Description
This is a prospective clinical trial that aims to investigate the impact of thyroxine supplementation on the outcomes of pregnancies in women who have experienced recurrent pregnancy loss in the first...
Eligibility Criteria
Inclusion
- Women aged 18 to 40 years old.
- Diagnosis of recurrent pregnancy loss, defined as two or more pregnancy losses in the first trimester.
- Confirmed thyroid function test results with TSH levels either between 2.5 and 4 or higher than 4.
- Willing and able to give informed consent for participation in the study.
Exclusion
- Women who are currently taking thyroid medication before the study starts.
- Presence of other causes of recurrent pregnancy loss such as antiphospholipid syndrome, uterine abnormalities, genetic/chromosomal disorders, etc.
- Presence of other severe chronic diseases like heart disease, kidney disease, uncontrolled diabetes, etc.
- Known allergy or intolerance to thyroxine.
Key Trial Info
Start Date :
March 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 20 2023
Estimated Enrollment :
77 Patients enrolled
Trial Details
Trial ID
NCT06036576
Start Date
March 1 2022
End Date
July 20 2023
Last Update
September 14 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
AL-Elwiyah Maternity Teaching Hospital
Baghdad, Iraq, 10011