Status:

RECRUITING

Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums

Lead Sponsor:

Case Western Reserve University

Conditions:

Recession, Gingival

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The primary objective of this randomized clinical trial is to compare the mean root coverage achieved with Coronally Advanced Flap (CAF) + Connective Tissue Graft (CTG) (control) to Gingival Pedicle S...

Detailed Description

1. Research Scope: This study focuses on treatment of isolated gingival recession in mandibular incisors. Coronally advanced flap (CAF) with connective tissue graft (CTG) is the most predictable surgi...

Eligibility Criteria

Inclusion

  • Males and females of \> 18 years of age
  • Single Cairo's RT1 (Recession Type 1) and RT2 ( Recession Type 2) recession defects (≥3 mm in depth) in mandibular anterior teeth (Incisors).
  • Presence of identifiable cemento-enamel junction (CEJ)
  • Presence of a step ≤1 mm at the CEJ level and/or the presence of a root abrasion, but with an identifiable CEJ, will be accepted
  • Periodontally and systemically healthy patients
  • No contraindications for periodontal surgery and not taking medications known to interfere with periodontal tissue health or healing; and no prior periodontal surgery on the involved sites

Exclusion

  • Vaping, chewing tobacco or smoking \> 10 cigarettes per day
  • Uncontrolled Diabetes Mellitus (HbA1c \> 7)
  • Pregnancy and Lactation
  • Diseases affecting connective tissue metabolism
  • Long-term steroid use
  • Recession defects associated with caries
  • Teeth associated with pulpal pathology

Key Trial Info

Start Date :

May 19 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 30 2026

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT06037161

Start Date

May 19 2023

End Date

July 30 2026

Last Update

April 4 2025

Active Locations (1)

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1

Case Western Reserve University School of Dental Medicine

Cleveland, Ohio, United States, 44106