Status:

NOT_YET_RECRUITING

Novel Cardiovascular Biomarkers in Patients With Kidney Disease

Lead Sponsor:

Liverpool University Hospitals NHS Foundation Trust

Conditions:

Haemodialysis Complication

Major Adverse Cardiac Events

Eligibility:

All Genders

18+ years

Brief Summary

Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work as well as they should. End-stage kidney failure (ESKD) is the final, irreparable stage of chronic kidney disease (C...

Detailed Description

Currently, there is no specific approach to stratify CV risk in HD patients; therefore, patients are not offered targeted preventative interventions. This novel project will characterise circulating b...

Eligibility Criteria

Inclusion

  • Patients aged≥45 years (or ≥18 with a history of diabetes). b. Cases: Incident haemodialysis patients c. A comparative arm of peritoneal dialysis patients and CKD 3-4 (not on dialysis) with hypertension as a key risk factor for CVD.
  • d. Capable of understanding the purpose and risks of the study, fully informed, and given informed consent.

Exclusion

  • Patients with pre-existing heart disease will be excluded.
  • Patients with active cancer.

Key Trial Info

Start Date :

November 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06037759

Start Date

November 1 2023

End Date

November 1 2026

Last Update

September 18 2023

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Novel Cardiovascular Biomarkers in Patients With Kidney Disease | DecenTrialz