Status:
RECRUITING
Improving Pulmonary Hypertension Screening by Echocardiography
Lead Sponsor:
Royal United Hospitals Bath NHS Foundation Trust
Collaborating Sponsors:
Janssen-Cilag Ltd.
Royal Free Hospital NHS Foundation Trust
Conditions:
Pulmonary Hypertension
Eligibility:
All Genders
18+ years
Brief Summary
This study aims to assess the application of the novel IMPULSE algorithm for the detection of pulmonary hypertension (PH) in those with a low or intermediate probability of PH according to the British...
Detailed Description
This is a prospective, multi-centre cross-sectional study with a planned 18 month longitudinal component. Participants will be recruited from patients referred for the first time for transthoracic ec...
Eligibility Criteria
Inclusion
- Unexplained breathlessness
- Risk factors for Pulmonary arterial hypertension (PAH), chronic thromboembolic pulmonary hypertension (CTEPH)
- Unexplained elevation of B-type natriuretic peptide (BNP/proBNP)
- Referred for catheterisation.
Exclusion
- ESC / BSE echo high probability of PH
- Known or suspected congenital heart disease
- Patients unlikely to benefit from management of PH or its underlying causes.
Key Trial Info
Start Date :
November 11 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 28 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06038149
Start Date
November 11 2023
End Date
February 28 2026
Last Update
November 21 2025
Active Locations (5)
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1
Royal United Hospital NHS Foundation Trust
Bath, Banes, United Kingdom, BA1 3NG
2
Golden Jubilee Hospital
Glasgow, Lanarkshire, United Kingdom, G81 4DY
3
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, South Yorkshire, United Kingdom, S10 2JF
4
Royal Papworth Hospital
Cambridge, United Kingdom, CB2 0AY