Status:

RECRUITING

Evaluation of Integrated Versus Parallel Connection for Renal Replacement Therapy in ECMO Patients

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Venoarterial Extracorporeal Membrane Oxygenation

Renal Replacement Therapy

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Extracorporeal membrane oxygenation (ECMO) is an extra-corporeal assistance used in case of respiratory or circulatory failure. In case of circulatory failure, ECMO is in the veno-arterial configurati...

Eligibility Criteria

Inclusion

  • Patients between 18 and 75 years of age
  • Patient on VA-ECMO who requires the initiation of continuous RRT during VA-ECMO treatment
  • Patient with a foreseeable length of stay in intensive care greater than 24 hours

Exclusion

  • Patient who does not have a vascular capital allowing for the insertion of a new dialysis catheter to administer RRT and therefore cannot be randomized to the parallel connection group
  • High pressures monitored on ECMO not allowing direct RRT catherter on ECMO
  • Pregnant, parturient, or breastfeeding women
  • Patient deprived of liberty by a judicial or administrative decision
  • Patient under psychiatric care
  • Patient subject to a legal protection measure (guardianship, curators)
  • Patient not affiliated to a social security system
  • Patient participating in another interventional research study in the field of extra purification renal

Key Trial Info

Start Date :

February 7 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

158 Patients enrolled

Trial Details

Trial ID

NCT06038162

Start Date

February 7 2024

End Date

September 1 2026

Last Update

March 4 2025

Active Locations (9)

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Page 1 of 3 (9 locations)

1

CHU de Bordeaux, GH Sud, Service d'anesthésie-réanimation cardiovasculaire, Hôpital cardiologique

Bordeaux, France

2

CHU de Clermont Ferrand, Pôle de médecine péri-opératoire/Chirurgie cardiaque, Hôpital Gabriel Montpied

Clermont-Ferrand, France

3

Centre Hospitalo Universitaire de Dijon, Unité Réanimation Cardio-Vasculaire,

Dijon, France, 21079

4

CHU de Grenoble, Service de réanimation cardiovasculaire et thoracique, Pôle anesthésie réanimation, Hôpital Nord

Grenoble, France