Status:
COMPLETED
Flurbiprofen Versus Aloe Vera Gel in the Treatment of Chronic Periodontitis in Smoking Patients.
Lead Sponsor:
Beirut Arab University
Conditions:
Periodontitis Chronic Generalized Severe
Eligibility:
All Genders
20-60 years
Phase:
PHASE4
Brief Summary
This study aims to evaluate clinically the efficacy of flurbiprofen gel in comparison to Aloe Vera gel as adjunctive to SRP in the reduction of periodontal pockets in patients with chronic periodontit...
Detailed Description
Complete medical and dental histories as well as informed consent will be collected from eligible participants, and periodontal charting will be done for them. Medical history and laboratory screenin...
Eligibility Criteria
Inclusion
- Inclusion criteria: 60 patients were selected who had clinical periodontal loss and radiographic bone loss of stage III/grade C with no history of systemic disease. They had at least 2 periodontal sites with a pocket depth of six mm or greater, radiographic evidence of bone loss extending to the middle third of the root, and clinical attachment loss of five mm or more. Eligible subjects were categorized as current smokers if they consistently smoked more than 10 cigarettes per day for a minimum of 5 years. Additionally, individuals with no record of undergoing any periodontal treatment within the six months preceding the study were considered for inclusion.
- Exclusion criteria: Patients with systemic illnesses such as diabetes mellitus or conditions that could potentially impair wound healing were excluded from participation. Additionally, individuals who were pregnant or lactating were not considered for inclusion in the study. Subjects who had been prescribed systemic antibiotics or non-steroidal anti-inflammatory drugs (NSAIDs) within the three months preceding the study were also excluded. Furthermore, individuals with confirmed or suspected hypersensitivity to Flurbiprofen or aloe Vera, the focus of the investigation, were not included in the study population.
Exclusion
Key Trial Info
Start Date :
September 30 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 19 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06041178
Start Date
September 30 2022
End Date
July 19 2023
Last Update
September 18 2023
Active Locations (1)
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1
Beirut Arab University
Beirut, Lebanon