Status:
COMPLETED
Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair
Lead Sponsor:
Cairo University
Conditions:
Peptic Ulcer Perforation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aims to evaluate safety and benefits of early oral feeding compared to traditional delayed oral feeding in patients undergoing perforated peptic ulcer repairs. Study population \& Sample si...
Detailed Description
Study Design: This study is a single-center, prospective, parallel arm, randomized controlled trial. Patients will be randomly assigned in 1:1 ratio to receive either delayed oral feeding or early or...
Eligibility Criteria
Inclusion
- \- All consecutive patients, of age 18 years and above, who were
- presented to the emergency surgical team and were diagnosed with perforated duodenal ulcer by surgicalteam, were recruited and assessed for eligibility.
Exclusion
- • Preoperative refractory septic shock on admission.
- Delayed presentation more than 24 hours.
- The presence of neuropsychiatric disease, pregnant and lactating women.
- Predisposing factors for impaired wound healing (e.g., currently using immunosuppressive agents, or chronic use of steroids), the presence of HIV.
- American society of anesthesiologists grade iii/iv, or had an alternative perioperative diagnosis.
- Intraoperatively, after randomization, patients were excluded based on the following criteria: perforated duodenal ulcer ≥20 mm, consistent with malignant ulcers.
Key Trial Info
Start Date :
March 2 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06042933
Start Date
March 2 2023
End Date
November 1 2024
Last Update
August 29 2025
Active Locations (1)
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1
Cairo University
Cairo, Egypt, 11511