Status:
RECRUITING
CNS Changes Following Upper Limb Loss
Lead Sponsor:
University of Zurich
Collaborating Sponsors:
ETH Zurich
Conditions:
Amputation, Congenital
Upper Limb; Amelia
Eligibility:
All Genders
18-75 years
Brief Summary
The objective of this study is to better understand the structural and functional changes that the central nervous system (CNS) undergoes following congenital upper limb loss. The focus is on the brai...
Eligibility Criteria
Inclusion
- Inclusion Criteria - Patients:
- Age 18-75
- Upper-limb congenital amputees with complete absence of a hand
- Signed informed consent
- Exclusion Criteria - Patients:
- Contraindications to magnetic resonance imaging
- Neurological impairment of body function impairments not induced by spinal cord injury
- BMI \> 40
- Pregnancy
- Claustrophobia
- Inclusion Criteria - Healthy subjects:
- Age 18-75
- Signed Informed consent
- Exclusion Criteria - Healthy subjects:
- Contraindications to magnetic resonance imaging
- Pregnancy
- Neurological illness
- Impairment of body function induced by a congenital upper-limb amputation
- Claustrophobia
- BMI \> 40
Exclusion
Key Trial Info
Start Date :
July 5 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2027
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT06043518
Start Date
July 5 2023
End Date
June 30 2027
Last Update
November 19 2025
Active Locations (1)
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1
Balgrist Campus
Zurich, Canton of Zurich, Switzerland, 8008