Status:
NOT_YET_RECRUITING
The Influence of Primary HIV-1 Drug Resistance Mutations on Immune Reconstruction in PLWH
Lead Sponsor:
Medical University of Warsaw
Conditions:
Hiv
AIDS
Eligibility:
All Genders
18-100 years
Brief Summary
Since the reasons for differential immune reconstitution in HIV-infected patients are still not fully understood, we considered it reasonable to investigate whether the presence of primary HIV drug re...
Detailed Description
Untreated HIV infection leads to progressive and permanent impairment of the immune system, and the successive loss of peripheral blood CD4+ T lymphocytes results in progression to AIDS. Effective ant...
Eligibility Criteria
Inclusion
- HIV-1 confirmed infection
- ART naive patients \> 18 years
- virological suppression after 6 months of ART
- available results of HIV genotyping before the start of ART
Exclusion
- hematologic neoplasms
- use of chemotherapy, immunosuppressive drugs and other myelotoxic agents
- lack of patient's consent to participate in the study
Key Trial Info
Start Date :
September 30 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2028
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06044792
Start Date
September 30 2023
End Date
January 1 2028
Last Update
September 21 2023
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