Status:

RECRUITING

Internet-Delivered Psychological Treatment for Cancer Survivors

Lead Sponsor:

Karolinska Institutet

Collaborating Sponsors:

Region Stockholm

Conditions:

Cancer Survivors

Anxiety

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Negative psychological effects of cancer are common, but cancer survivors are rarely offered structured psychological treatment. Internet-delivered treatments have shown some promise, but specific tre...

Eligibility Criteria

Inclusion

  • Cancer survivor at least 0.5 years after main therapy
  • Clinically significant anxiety or depression (Patient Health Questionnaire 9 \[PHQ-9\]≥10, or Generalized Anxiety Disorder 7 \[GAD-7\]≥8, or 9-item Fear of Cancer Recurrence Inventory \[FCRI-9\]≥16)
  • At least 18 years old
  • Resident of Region Stockholms, Västra Götalandsregionen, or Region Skåne, Sweden (listed and de facto)
  • Sufficient technical knowledge and knowledge of the Swedish language to take part in a text-based online treatment
  • Continuous access to an electronic device that can be used to access the study web platform

Exclusion

  • Recurrent thoughts of suicide, as based on clinical judgement aided by the structured interview and the self-report version of the Montgomery-Åsberg Depression Rating Scale (MADRS-S) item 9
  • Severe medical condition (e.g., very poor prognosis, stage IV cancer), severe psychiatric disorder (e.g., psychotic disorder, bipolar disorder, or severely debilitating substance use disorder, severe depression), or medical treatment (e.g., chemotherapy, immunotherapy, radiotherapy) that makes the treatment unfeasible
  • Other ongoing psychological treatment
  • Continuous psychotropic medication not stable for the past 4 weeks, or not expected to remain stable during the treatment period
  • Planned absence for more than one week of the intended treatment period
  • No complete the pre-treatment assessment

Key Trial Info

Start Date :

April 10 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2031

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT06046586

Start Date

April 10 2025

End Date

December 31 2031

Last Update

November 21 2025

Active Locations (1)

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1

Karolinska Institutet

Stockholm, Sweden

Internet-Delivered Psychological Treatment for Cancer Survivors | DecenTrialz