Status:
COMPLETED
PREDICTIVE ABILITY OF A PANEL OF BIOMARKERS IN SALIVA IN HEALTHY AND PERIODONTALLY AFFECTED SUBJECTS
Lead Sponsor:
Universidad Complutense de Madrid
Conditions:
Periodontitis
Saliva
Eligibility:
All Genders
18+ years
Brief Summary
Objective: The main aim of this cross-sectional clinical study is to evaluate the predictive ability of a panel of salivary biomarkers in determining periodontal health status. Material and methods: ...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Adults (≥ 18-year-old)
- Being able to sign an informed consent form
- Willing to participate in this observational investigation
- Diagnosed as periodontally healthy, gingivitis, treated periodontitis patient (stable / unstable), periodontitis stages I \& II, or periodontitis stages III and IV (Papapanou et al. 2023)
- Exclusion criteria:
- Patients fitting to all the above inclusion criteria will be excluded from the study if unable to attend to the study-related procedures or if one or more of the following systemic or local exclusion criteria will be found at any time through the study:
- Systemic exclusion criteria
- Un-controlled diabetes (HbA1c \>7)
- Compromised general health status (≥ASA III);
- Drug abuse, alcohol abuse, or smoking \> 10 cigarettes a day;
- Chronic use of corticosteroids, NSAIDs, or immune modulators (any type/dose);
- No recent Asthma, hayfever, allergies, severe intolerances
- Mouth piercing, xerostomia
- Pregnant or nursing women.
- Local exclusion criteria
- History of antibiotic intake within the last 30 days
- History of periodontal/mucogingival surgery within the last 6 months.
Exclusion
Key Trial Info
Start Date :
October 23 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06047132
Start Date
October 23 2023
End Date
June 30 2024
Last Update
June 26 2025
Active Locations (1)
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1
Faculty of Dentistry, University Complutense of Madrid (UCM)
Madrid, Madrid, Spain, 28040