Status:
COMPLETED
EUS-guided Versus Percutaneous Ultrasound-guided Biopsy for Parenchymal Liver Disease
Lead Sponsor:
Institute of Liver and Biliary Sciences, India
Conditions:
Liver Cirrhosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Liver biopsy may be indicated in various clinical scenarios to help diagnose and manage liver diseases. Endoscopic ultrasound (EUS) liver biopsy and percutaneous USG guided liver biopsy are two method...
Detailed Description
Aim and Objective - EUS-LB with a 19G Franseen needle is non-inferior to PC-LB with a 18G BioPince Needle, with regards to total specimen length and diagnostic adequacy. Hypothesis - i. EUS-LB with a...
Eligibility Criteria
Inclusion
- Patients \> 18 years of age.
- Eligibility for deep sedation with propofol.
- Undergoing liver biopsy for diagnosis/evaluation/staging.
Exclusion
- Coagulopathy, defined by platelet count \< 70,000/mL and/or INR \> 1.7.
- Inability to discontinue anticoagulation or antiplatelet agents for 5 days prior to the procedure.
- Presence of unrelieved biliary obstruction.
- Presence of ascites.
- Suspected or known hepatic malignancy.
- Hypertensive patients with uncontrolled blood pressure. (SBP \>150 and/or DBP\>100mmHg)
- Medically unfit for sedation.
- Inability to provide informed consent.
- Cannot understand Hindi or English should be excluded since they will not be able to reply objectively to questionnaire.
Key Trial Info
Start Date :
November 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2025
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06047327
Start Date
November 1 2023
End Date
November 30 2025
Last Update
January 5 2026
Active Locations (1)
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1
Institiute of liver and biliary sciences
New Delhi, India, 110070