Status:
RECRUITING
Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome
Lead Sponsor:
Shanghai 10th People's Hospital
Conditions:
Polycystic Ovary Syndrome
Eligibility:
FEMALE
18-45 years
Brief Summary
The investigators collected clinical data and serum samples of patients with polycystic ovary syndrome (PCOS) in this study, used statistical software such as SPSS for date analysis, and used experime...
Eligibility Criteria
Inclusion
- Female aged 18- 45;
Exclusion
- Female patients younger than 18 years old or older than 45 years old;
- Ovulatory disorders caused by premature ovarian failure, pituitary amenorrhea, hypothalamic amenorrhea, and thyroid dysfunction;
- Congenital adrenal hyperplasia, reservoir Hin syndrome, hyperprolactinemia, adrenal tumors and other diseases that cause hyperandrogenism;
- Abnormal liver or renal function((≥ 3 times of the upper limit of normal range)
- Type 1 diabetes, single gene mutation diabetes, or pancreatic damage Diabetes or other secondary diabetes caused by diabetes;
- History of malignant tumors;
- Severe infection, severe anemia, neutropenia and other systemic chronic diseases;
- Undergo total hysterectomy or ovarian adnexectomy;
- Mental illness, dementia or other cognitive behavioral problems;
- Use hypoglycemic drugs that may affect insulin resistance and androgen levels in the last 3 months, including thiazolidinediones, metformin, SGLT-2, and acarbose and GLP-1RA and other drugs;
- Use letrozole, clomiphene, oral contraceptives, glucocorticoids, gonadotropins, gonadotropin-releasing hormone agonists, anti-androgens (spironolactone, Cyproterone acetate, flutamide, etc.) and other drugs for the treatment of PCOS.
Key Trial Info
Start Date :
September 18 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 30 2025
Estimated Enrollment :
3000 Patients enrolled
Trial Details
Trial ID
NCT06047574
Start Date
September 18 2023
End Date
July 30 2025
Last Update
March 19 2024
Active Locations (1)
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1
Department of Endocrinology, Shanghai Tenth People's Hospital
Shanghai, Shanghai Municipality, China, 200070