Status:
RECRUITING
Impact of Atrial Fibrosis Surface Area on the Occurrence of Atrial Fibrillation in Patients With Ischemic Stroke of Undetermined Origin: a Prospective Cardiac MRI Pilot Study.
Lead Sponsor:
Centre Hospitalier Universitaire Dijon
Conditions:
Stroke
Implantation of an Implantable Cardiac Monitor
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Atrial fibrillation is a cardiac arrhythmia most often originating in the left atrium, causing anarchic electrical activity and thus a loss of atrial contraction. This increases the risk of stroke thr...
Eligibility Criteria
Inclusion
- Patient who has provided free, written and informed consent
- Patient of legal age
- Patient with cryptogenic ischemic stroke within 30 days of inclusion, documented by brain imaging (cerebral angioscan or cerebral MRI)
- Patients scheduled for implantable loop recorder implantation within 3 months of ischemic stroke in search of silent AF:
- cryptogenic ischemic stroke or stroke with probable cardioembolic cause
- no history of atrial fibrillation
- no long-term anticoagulant therapy
- with life expectancy \>12 months
Exclusion
- Person not affiliated to national health insurance
- Person under legal protection (curatorship, guardianship)
- Person under court order
- Pregnant, parturient or breast-feeding
- Adult unable to give consent
- Patient diagnosed with AF during stroke assessment
- Patient with a contraindication to MRI or gadolinium injection:
- Severe renal impairment (\<30ml/min Cockroft clearance due to gadolinium injection)
- Claustrophobia / contraindication to MRI (metal implant not MRI compatible)
- History of hypersensitivity to gadoteric acid or gadolinium-based contrast agents, and to meglumine
- Uncontrolled asthma
Key Trial Info
Start Date :
January 31 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2029
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06047782
Start Date
January 31 2024
End Date
January 1 2029
Last Update
May 8 2024
Active Locations (1)
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1
Chu Dijon Bourgogne
Dijon, France